Endocrine Abstracts

Introduction: The incidence of hyperthyroidism is influenced by iodine nutrition. Sweden is a long-term iodine sufficient (IS) area with an iodination fortification program since 1936.Methods: In 2003–2005, all referred cases of subclinical (SH) and overt hyperthyroidism (OH) were registered from a targeted population of 631239 individuals in Gothenburg. Information on age, gender, etiology, smoking, thyroid associated ophtalmopathy (TAO), thyroid h...

Context: In untreated acromegalic patients, decreased cognitive functioning is reported to be associated with the degree of GH and IGF1 excess. Whether previous GH excess or current medical treatment for acromegaly specifically affects cognition remains unclear.Objective: To compare cognitive functioning in patients who are treated for acromegaly and non-functioning pituitary adenomas (NFA). In addition, we assessed the influence of prolonged medical tre...

Objective: To assess the influence of use of long-acting somatostatin analogs on long-term health-related quality of life (HR-QoL) in relation to disease control in patients surgically-treated for acromegaly.Design: Cross-sectional study in two University Medical Centers in The Netherlands.Patients: One hundred and eight patients (47 m/61 f, mean age 54±11 years) with a minimal follow up period of 1 year after pituitary surger...